Bioactivity: β-Glucuronidase-IN-2 is a potent E. coli β-glucuronidase inhibitor with an IC 50 value of 0.24 μM, an K i value of 1.09 μM. β-Glucuronidase-IN-2 shows antiproliferative activity. β-Glucuronidase-IN-2 has the potential for the research of anti-cancer and anti-inflammatory therapies [1].